中华卷柏的化学成分研究

Chemical constituents of Selaginella sinensis

目的 研究中华卷柏Selaginella sinensis的化学成分。方法 利用Diaion HP-20，Toyopearl HW-40，硅胶柱等柱色谱技术进行分离纯化。根据化合物的理化性质和光谱数据鉴定结构。结果 分离并鉴定了11个化合物的结构，分别为：β-谷甾醇（Ⅰ）、香荚兰酸（Ⅱ）、（7S，8R）-4，9，9′-三羟基-3，31-二甲氧基-7，8-二氢苯并呋喃-1′-丙基新木脂素（Ⅲ）、丁香脂素（Ⅳ）、（一）-松脂素（Ⅴ）、松脂酚-4-O-β-D-葡萄糖苷（Ⅵ）、丁香脂素-4，4′-O-二-β-D-葡萄糖苷（Ⅶ）、β-甲基-D-吡喃木糖苷（Ⅷ）、β-甲基-D-吡喃阿拉伯糖苷（Ⅸ）、扁柏双黄酮（Ⅹ）、阿曼托双黄酮（Ⅺ）。结论 化合物Ⅱ～Ⅸ均为首次从该植物中分离得到。

Objective To study the chemical constituents from Selaginella sinensis. Methods The compounds were isolated with Diaion HP-20, Toyopearl HW-40, silica gel column chromatography. The structures of these compounds were identified by physicochemical properties and spectral analyses. Results Eleven compounds were isolated from the 70% acetone-extracts and their structures were identified as sitosterol （ Ⅰ ）, vanillic acid （ Ⅱ ）, （7S, 8R）-4, 9, 9′-trihydroxy-3, 3′-dimethoxy-7, 8-dihydrobenzofuran-1′-propylneolignan （ Ⅲ ）, syringaresinol （ Ⅳ）, （—）-pinoresinol （ Ⅴ ）, pinoresinol-4-O-β-D-glucopyranoside （ Ⅵ ）, syringaresinol-4, 4′-O-di-β-D-glucopyranoside （ Ⅶ）, β-methyl-D-xylopyranoside （Ⅷ）, methyl-D-arabinopyranoside （ Ⅸ ）, hinokiflavone （ Ⅹ）, and amentoflavone （ Ⅺ ）. Conclusion Compounds Ⅱ—Ⅸ are isolated from this plant for the first time.