老年急性冠脉综合征患者从有创治疗中获益的临床观察

Clinical observation of traumatic therapy in senium patients with acute coronary syndrome

目的:探讨老年急性冠脉综合征患者是否从有创治疗冠状动脉腔内成形术(PCI)及冠脉搭桥术(CABG)中获益。方法:200例老年(≥65岁)急性冠脉综合征患者,100例经冠脉造影后接受PCI或CABG治疗,为有创治疗组,其中PCI88例,CABG12例。100例接受药物治疗为药物治疗组。比较30d和6个月内急性心肌梗死发生率及30d和6个月内死亡发生率。结果:两组患者在基本情况(年龄、性别、吸烟、患糖尿病、高血压、陈旧性心肌梗死、左室射血分数)均无统计学差异(P>0.05)的前提下,30d和6个月内急性心肌梗死发生率及心源性死亡发生率有创治疗组均明显下降,两组比较均有统计学差异(P<0.05)。结论:老年急性冠脉综合征者应积极接受冠脉造影及有创治疗,要比从药物治疗中获益更多。

Objective To evaluate whether the aged could benefit from traumatic therapy, such as PCI and CABG, for acute coronary syndrome（ACS）, Methods Two hundred ACS patients（ ≥65 years old） diagnosed by coronary arteriongraphy were devided into traumatic therapy group [Group T, n = 100, including PCI （n = 88） and CABG （n = 12）] and drug therapy group （Group D, n = 100）. The acute myocardial infarction rate and the cardiac death rate were observed within 30 days and 6 months, respectively. Results Statistical difference for the acute myocardial infarction rate and the cardiac death rate is observed between Group T and Group D （P 〈 0.05）, which the former of was significantly lower than that in latter, although there is no statistical difference between the basic conditions （age, sex, smoking, diabetes, hypertension, left ventricle ejection fraction） of the two groups （P 〉 0.05）. Conclusions The senium patients with ACS may accept traumatic therapy and will get more benefit than from drug therapy.