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医院获得性急性肾衰病因及预后分析 被引量:1

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摘要 目的:医院获得性急性肾功能衰竭(HAARF)和社区获得性急性肾功能衰竭(CAARF)进行比较。分析医院获得性急性肾功能衰竭(HAARF)的临床特点、病因和影响预后的危险因素。方法:回顾性调查我院1991年1月—2004年7月200例急性肾功能衰竭病人分两组既往无肾脏病史住院期间发生的急性肾衰为 HAARF 组和入院前就有急性肾衰为 CAARF 组。118例 CAARF 做为对照组与82例 HAARF 组进行病因、病死率和预后危险因素的比较,评价 HAARF。结果:ARF 病例200例,其中男性126例,女性74例,男女比值为1.7:1;平均年龄44.1±17.8岁(8—89岁)。HAARF82例,死亡31例,病死率37.8%,CAARF118例,死亡16例,病死率13.56%,经比较HAARF 病死率明显高于 CAARF 组,有显著统计学意义(P<0.001)。6种因素参与急性肾衰的死亡危险因素分析,结果显示,HAARF 组发病年龄、少尿、昏迷发生率和合并感染率明显高于 CAARF 组(P<0.05)。而低血压,机械通气等因素两组间无差异(P 均>0.05)。HAARF 主要病因以术后并发最多见,其次为感染、药物、慢性肝病和心脏病。结论:(1)HAARF 组病死率明显高于 CAARF 组。(2)HAARF 最常见病因为大手术后并发,其次为各种感染。(3)年龄、少尿、昏迷和合并感染是影响预后的重要危险因素。(4)预防 HAARF 的关键在于针对病因和危险因素进行干预和治疗。
出处 《新疆医学》 2007年第6期30-33,共4页 Xinjiang Medical Journal
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