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游离脂肪酸在2型糖尿病动脉粥样硬化发生中的作用

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摘要 2型糖尿病大血管病变主要病理基础是动脉粥样硬化,它影响2型糖尿病患者生活质量并对患者的生命构成威胁。近年来的研究发现游离脂肪酸可能参与了2型糖尿病动脉粥样硬化的发生发展。其在内皮细胞损伤、动脉粥样硬化发生发展中的作用得到越来越多的关注。本研究通过对糖尿病患者与非糖尿病患者的对比研究,旨在探讨FFA在2型糖尿病动脉粥样硬化发生中的地位。
出处 《新疆医学》 2007年第6期55-58,共4页 Xinjiang Medical Journal
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参考文献7

  • 1Steinberg HO Paradisi G Hook G et al.Fre e fatty acid impairs insulin-mediatedvasodilation and nitric oxide production.Diabetes.2000;49.1231-1238.
  • 2Trevor J.Biden,Darren Robinson,et al,Chronic Effects of Fatty Acids on Pancreatic B-Cell Function:New Insights From Functional Genomics.Diabetes 2004(53):S159-S165.
  • 3钱荣立.关于糖尿病的新诊断标准与分型[J].中国糖尿病杂志,2000,8(1):5-6. 被引量:2314
  • 4余叶蓉,Zhu Jinsu,Wu Yonggang,Alain D.Baron.胰岛素对游离脂肪酸所致大鼠内皮依赖性血管舒张功能损害的影响[J].中华医学杂志,2002,82(6):422-425. 被引量:13
  • 5Zeng G Nystrom FH Ravichandran LV et al.Roles for insulin receptor PI3-kinaseand Akt in insulin-signaling patuways related to production of nitric oxide in humanvascular endothelial cells Circulation.2000;101.1539-1545.
  • 6Boden G,Carnell L H.Nutritional effects of fat on carbohydrate metabolism.Best Pratt ResClin Endocrinol Metab,2003,17:399-410.
  • 7Paul Holvoet,Stephen B et al,The Metabolic Syndromc,Circulating Oxidized LDL,and Riskof Myocardial Infarction in Well-Functioning Elderly Peoplc in the Health,Aging,and BodyComposition Cohort.Diabetes 2004,(53):1068-1073.

二级参考文献6

  • 1Steinberg HO,Paradisi G,Hook G,et al.Free fatty acid impairs insulin-mediated vasodilation and nitric oxide production[].Diabetes.2000
  • 2Zeng G,Nystrom FH,Ravichandran LV,et al.Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells[].Circulation.2000
  • 3Reaven GM,Syndrom X.6 years later[].Journal of Internal Medicine.1994
  • 4Hsueh WA,Law RE.Insulin signaling in the arterial wall[].The American Journal of Cardiology.1999
  • 5Dresner A,Laurent D,Marcucci M,et al.Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-Kinase activity[].The Journal of Clinical Investigation.1999
  • 6Steinberg HO,Tarshoby M,Monestel R,et al.Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation[].The Journal of Clinical Investigation.1997

共引文献2325

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