2型糖尿病下肢血管并发症患者血清hs—CRP及IL-6的检测意义

On the Significance of hs--CRP and IL-6 Testing in Type--2 Diabetes and Diabetic Angiopathy

目的：探讨血清超敏C反应蛋白（hs—CRP）和IL-6检测在2型糖尿病及其血管并发症中的临床价值。方法：采用散射免疫比浊法检测38例2型糖尿病患者及33例2型糖尿病合并下肢血管病变患者血清hs—CRP，同时用Elisa法检测IL-6，并与对照组比较。结果：2型糖尿病患者及2型糖尿病合并下肢血管病变患者血清hs-CRP和IL-6显著高于对照组（P〈0．01），2型糖尿病合并下肢血管病变患者血清hs—CRP和IL-6显著高于单纯2型糖尿病患者（P〈0．01）。结论：hs-CRP和IL-6在2型糖尿病并发下肢血管病变时发挥了一定的炎性作用，在预测糖尿病并发下肢血管病变中具有重要的临床意义。

Objective.. To explore the clinical significance of hs--CRP and IL-6 testing in type 2 diabetes and other complication. Methods： We use nephelometry to test hs-CRP of 38 eases of type 2 diabetes patients and 33 eases of those who are affected by complication of diabetic angiopathy and use Elisa to test IL- 6, then we make a comparison with the controls. Results.. Both hs-CRP and IL-6 of the experiment are significantly higher than those of the controls and hs--CRP and IL-6 of the diabetic angiopathy patients are significantly higher than those of the diabetes patients. Conclusion： Hs--CRP and IL-6 play an important role in testing diabetes and diabetic angiopathy and have important clinical significance in forecasting diabetic angiopathy.