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黑腹果蝇蛋白质编码区碱基分布与起始密码子及终止密码子的关系 被引量：1

The relation bertween base distribution in protein coding regions and initiation codons or stop codons in Drosophila melauogaster
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摘要 对黑腹果蝇染色体上基因组进行统计分析,结果表明,蛋白质编码区(CDS)碱基分布具有不均匀性.对单核苷酸、双核苷酸及密码子的使用进行统计,结果表明,与起始密码子对应的组分中,NTG的使用倾向值相对高,终止密码子(TGA,TAA,TAG)对应的组合使用倾向值相对很低.由此得出结论:起如密码子对蛋白质编码区碱基的使用有一定的影响,终止密码子对蛋白质编码区碱基的使用具有较强限制作用. The distribution of bases at three codon positions is heterogeneous based on statistical analysis of Drosophila melauogaster chromosomes. Statistics analysis for the usage of the bases, dinucleotides and codons shows that the tendency of NTG is relatively high, and the bases, dinucleotides and codons with low contents are just associated with those in the stop codons. The conclusion is that the initiation codon has certain influence on base distribution in the protein coding regions, and the bases related to the stop codons are strictlyconstrained to be used.
作者 蔡禄 崔向军 刘辉
机构地区 内蒙古科技大学生物与化学工程学院
出处 《内蒙古科技大学学报》 CAS 2007年第4期341-344,共4页 Journal of Inner Mongolia University of Science and Technology
基金 国家自然科学基金资助项目(60761001) 内蒙古自然科学基金重点资助项目(200508010102)
关键词 起始密码子 终止密码子 碱基分布 黑腥果蝇 限制作用 irritation condon stop codon base distribution Drosophila melauogaster restricive action
分类号 Q811.4 [生物学—生物工程]
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参考文献11

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共引文献39

同被引文献20

  • 1翁景然,张宏,耿美英,张成岗.真核基因起始与终止密码子旁侧序列特征分析[J].生物信息学,2004,2(4):10-14. 被引量：6
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内蒙古科技大学学报
2007年 第4期

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