黄芪注射液联合川芎嗪注射液治疗冠心病不稳定型心绞痛46例临床观察

Effect of Huangqi Injection Combined with Tetramethylpyrazine Injection for Unstable Angina Pectoris in Coronary Heart Disease:An Observation of 46 Cases

目的:观察黄芪注射液联合川芎嗪注射液治疗冠心病不稳定型心绞痛(UA)的临床疗效。方法:将92例患者随机分为2组各46例,在常规西药治疗基础上,治疗组给予黄芪注射液联合川芎嗪注射液治疗;对照组给予复方丹参注射液治疗,疗程均为2周。结果:治疗后心绞痛总有效率治疗组为82.6%,对照组为67.4%,2组比较,差异有显著性意义(P<0.05)。治疗后2组心电图指标、心绞痛发作次数、心绞痛持续时间以及硝酸甘油用量均有改善,与治疗前比较,差异有显著性意义(P<0.05);治疗后2组比较,差异亦有显著性意义(P<0.05),治疗组疗效优于对照组。结论:黄芪注射液联合川芎嗪注射液治疗UA疗效肯定。

Objective:To observe the therapeutic effect of Huangqi Injection(HJ) combined with tetramethylpyrazine injection(TI)for unstable angina pectoris(UAP)in coronary heart disease(CHD). Methods:Ninety-two patients were equally randomized into two groups. Both of the two groups received routine western medicine,and the con- trol group was treated with Compound Danshen Injection and the treatment group received HJ combined with TI additionally. The treatment lasted 2 weeks. Results:The total ef- fective rate for angina pectoris was 82.6% in the treatment group and 67.4% in the con- trol group,the difference being significant(P<0. 05). After treatment,parameters of electrocardiogram,onset frequency and duration of angina pecloris,and the dosage of nitroglycerin were improved in the two groups(P<0. 05 compared with those before treatment). The differences of the above parameters between the two groups were also sig- nificant(P<0. 05). Conclusion:Huangqi Injection combined with tetramethylpyrazine injection has certain effect for unstable angina peetoris in coronary heart disease.