期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

B型脑钠肽测定在急性心肌梗死中的临床意义 被引量：5

下载PDF
导出
摘要 目的探讨急性心肌梗死(AMI)患者血浆中B型脑钠肽(B typenatriureticpeptide,BNP)水平变化的临床意义。方法选择住院患者60例,其中40例为急性心肌梗死患者(AMI组间与A组),20例为冠状动脉造影正常的对照组(E组)。根据心功能Killip分级将患病组分为,Killip1级(K1组)15例,Killip2级(K2组)12例和Killip3级(K3组)13例及Killip4级(K4组)。结果AMI心功能Killip3级组、Killip2级组及Killip1级组血浆BNP浓度分别高于Killip2级组、Killip1级组和对照组(P<0·05,P<0·05,P<0·01);冠脉3支病变组BNP浓度高于1支病变组(P<0·05)。结论患者心衰越重BNP的水平越高,BNP是反映心功能不全的有效指标,BNP可以作为急性冠脉综合征患者判断心功能和评估愈后的指标。
作者 郭宏怡 田颖 刘肆仁
机构地区 北京市第六医院心内科(内三)
出处 《中国实用医药》 2008年第15期140-141,共2页 China Practical Medicine
关键词 B型脑钠肽 急性心肌梗死 临床分析 治疗方法
分类号 R542.22 [医药卫生—心血管疾病]
  • 相关文献

参考文献7

  • 1徐丽,陈兰英.利钠肽结构、受体的生理和病理作用[J].中国病理生理杂志,2004,20(8):1517-1521. 被引量：13
  • 2[2]Mukoyama,Nakao K,Hosoda K,et al.Brain natriuretic peptide as a novel cardiac hormon inhumans.J Clin Invest,1991,87:1402-1412.
  • 3[3]Richards A,Crozier I,Yandle T,et al.Brain natriuretic fact or regional plasma concentrations andcorrelations with haemody namicstatein cardiac disease.Br Heart J,1993,69:414-417.
  • 4杜同信,王自正,王书奎,罗骏.AMI患者血浆BNP,ET,CRP,ANP水平变化与临床观察分析[J].放射免疫学杂志,2004,17(1):6-7. 被引量：18
  • 5[5]Arakawa N,Nakamura M,Aoki H,et al.Relation ship between plasma level of brain natriuretic peptide and myocardial infarct size.Cardiology,1994,85:334-340.
  • 6[6]Horio T,shimada K,Kohno M,et al.Serial changes in atria and brain natriuretic peptides in patients with acute myocardial infartion treated with early coronary angioplasty.Am heart J,1993,126:293-299.
  • 7[7]Hunt PJ,Richards AM,Nicholls MG,et al.Immunoreactive amino terminal pro-brain natriuretic peptide(NT PROBNP):a new marker of cardiacim pairment.Clin Endocrinol(Oxf)1997,47:287-296.

二级参考文献36

  • 1[1]Ridker P M, Cushman M, Stampfre MJ, et al. Plasma concentration of C-reactive protein and risk of developing peripheral vascular. Circulation, 1998, 97:425.
  • 2[2]Ridker PM, Rifai N, Pfeffer MA, et al. Inflammation, pravastatin and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Circulation, 1998, 98(9):839.
  • 3[3]Anzai T, Yoshikawa T, Shiraki H, et al. C-Reactive protein as a predictor of expansin and cardiac rupture after a first Q-wave acute myocardial infarction. Circulation, 1997,96(3):778.
  • 4[4]Arakawa N, Nakamura M, A oki H, et al. Relationship between plasma level of brain natruretic peptide and myocardial infarct size. Cardiology 1994, 85:334.
  • 5[5]Nicholls MG. The natriuretic peptides in heart failure. J Intern Med, 1994, 235:515.
  • 6[6]Alberola AM, Revert F, Moya A, et al. Intravenous BQ-123 and phosphoramidon reduce ventricular ectopic beats and myocardial infarct size in dogs submitted to coronary occlusion and reperfusion. J Gen Pharmacol, 2000, 35(3):143.
  • 7de Bold AJ, Borenstein HB, Veress AT, etal. A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats [J]. Life Sci, 1981, 28(1):89-94.
  • 8Flynn TG, de Bold ML, de Bold AJ. The amino acid sequence of an atrial peptide with potent diuretic and natriuretic properties [J]. Biochem Biopbys Res Commun, 1983, 117(3) :859 - 865.
  • 9Kangawa K, Fukuda A, Kubota I, et al. Human atrial natriuretic polypeptides (hANP): purification, structure synthesis and biological activity [J]. J Hypertens Suppl, 1984, 2(3):S321 - S323.
  • 10Nemer M, Lavigne JP, Drouin J, et al. Expression of atrial natriuretic factor gene in heart ventricular tissue [ J]. Peptides, 1986, 7(6):1147- 1152.

共引文献29

同被引文献30

  • 1汤学民,马江涛,王元彬.589例超敏C-反应蛋白检测结果的临床分析[J].实用医技杂志,2006,13(2):182-183. 被引量：4
  • 2白春洋,孙建华,赵耀亭,雷索苹.高敏C-反应蛋白在炎症性疾病中的临床意义[J].河南职工医学院学报,2006,18(1):52-54. 被引量：13
  • 3赵雪燕,杨跃进,张健,党爱民,倪新海,黄洁,康晟,马卫华,赵冬云.B型利钠肽在诊断左心衰竭中的价值[J].中华医学杂志,2006,86(17):1165-1169. 被引量：97
  • 4Michael G,Petersen W,Daniel B. Natriuretic peptides in the diagnosis and management of heart failure[J]. CMAJ, 2006,175(6) : 611-617.
  • 5Michael G,Petersen W, Daniel B.Natriuretic peptides in the diagnosis and management of heart failure [J].CMAJ,2006,175 (6):611- 617.
  • 6徐庆科,刘虹.曲美他嗪治疗冠心病心力衰竭临床研究[J].山东医药,2007,47(32):61-62. 被引量：9
  • 7Remme WJ,Swedbeng K. Comprehensive guidelines for the diagnosis and treatment of chronic heart failure.Task force for the diagnosis and treatment of chronic heart failure of the European society of cardiology[J].European Journal of Heart Failure,2002,(01):11-22.
  • 8Yamaguchi H,Yoshida J,Yamamoto K. Elevation of plasma brain natriuretic peptide is a hallmark of diastolic heart failure independent of ventricular hypertrophy[J].Journal of the American College of Cardiology,2004,(01):55-60.
  • 9周新;府伟灵.临床生物化学与检验[M]北京:人民卫生出版社,2007254.
  • 10Herzog WR,Farb A. Severe coronary artery disease:is there a place for percutaneous coronary intervention[J].Pol ch Med Wewn,2009,(06):397-402.

引证文献5

二级引证文献48

中国实用医药
2008年 第15期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部