2Scheen AJ, Letiexhe MR, Lefebvre PJ. Short administration of metformin improves insulin sensitivity in android obese subjects with impaired glucose tolerance[ J ]. Diabet Med 1995 ; 12( 11 ) : 985 - 989.
3UK Prospective Diabetes Study Group. Effect of intensive blood - glucose control with metformin on complications in overweight patients with type 2 diabetes[J], Lancet 1998;325(9131):854 - 865.
4Yki- Jarvinen H, Kauppila M, Kujansuu E, et al. Comparison of insulin regimens in patients with non - insuhn - dependent diabetes mellitus[J]. N Engl J Med 1992;327(20) : 1426-1433.
5Pan XR, Li GW, Hu YH, et al. Effects of diet and exercise in preventing NIDDM in eople with impaired glucose tolerance. The Da Qing IGT and Diabetes Study[J]. Diabetes Care 1997;20(4) : 537 - 544
6Tuomilehto J, Lindstrom J, Eriksson JG, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance[J]. N Engl J Med 2001;344(18): 1343 - 1350.
7Belfiore F, Iannelo S, volpicelli G. Insulin sensitivity indices calculated from basal and OGTT - induced insulin, glucose, and FFA level[J]. Mol Genet Metab 1998; 134 - 141.
8Wang My, Koyama K, Shimabukuro M, et al. OB - Rb gene transfer to leptin- resistane islets reversee diabetogenie phenotype[J ]. Proe Nail Aead Sei USA 1998;95(2) :714- 718.
9Gregorio F, Ambrosi F, Manfrini S, et al. Metformin plasma glucose and free fatty acides in type 2 diabtie out - patients: results of a clinical study[J].Diabetes Res clin Praet 1997;37(1):21-33.
10Rodriguez- Moctezuma JR, Robles - Lopez G, Lopez - Carmona JM, et al. Effects of metformin on the body composition in subjects with risk factors for type 2 diabetes[J] .Diabetes Metab 2005 ;7 (2) :189 - 192.
