白细胞介素6膜结合受体在子宫内膜异位症患者腹腔液中的表达及意义
被引量:1
摘要
子宫内膜异位症(内异症)是育龄期妇女的常见病和多发病,病因学涉及遗传、免疫、内分泌等多种因素。内异症患者腹腔液中巨噬细胞显著增多,并产生大量的细胞因子,如白细胞介素(interleukin,IL)6等,共同参与内异症的发生、发展。IL-6通过与其靶细胞表面的IL-6膜结合受体(membrane interleukin 6 receptor,mlL-6R)结合发挥其多种生物学功能,因此,IL-6的生物学活性不但与其本身的结构有关,很大程度上还取决于mlL-6R的结构与表达。目前人们对mlL-6R在内异症中的意义尚不了解。
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
2008年第5期368-369,共2页
Chinese Journal of Obstetrics and Gynecology
基金
浙江省卫生厅科学研究基金(2006A06)
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