儿童单纯性血尿37例临床和病理分析

Clinical anmd pathologicl analysis of isolated hematurian in 37 children

目的探讨小儿单纯性血尿的病理类型。方法对37例临床诊断为单纯性血尿的患儿进行肾组织活检,并进行光镜、电镜及免疫荧光检查。结果系膜增生性肾小球肾炎13例,肾小球轻微病变9例,IgA肾病8例,IgM肾病4例,局灶节段性肾小球硬化症3例。结论本组资料单纯性血尿最常见的病理类型是系膜增生性肾小球肾炎,其次是肾小球轻微病变及IgA肾病。

Objective To study the renal histological characteristics of isolated hematuria in children. Methods 37 children with isolated hematuria were performed renal biopsy. All biopsies were examined by light microscopy, electron microscopy and immunofluorescence. Results In this servies, the most common histological changes of isolated hematuria were as follows： 13 cases of mesangial proliferative glomerulonephritis, 9 cases of minor glomerular abnormalities, 8 cases of IgA nephropathy, 4 cases of IgM nephropathy and 3 cases of focal segmental glomerulosclerosis. Conclusion Mesangial proliferative glomerulonephritis is the most common pathological changes in isolated hematuria, followed by minor glomerular abnormalities and IgA nephropaihy.