葡萄胎患者血清β_2-MG的变化及临床意义

The changes and clinical significance of serum β_2-MG determination in patients with grape mole

目的：为探讨血清β_2-MG测定值在葡萄胎时的变化及临床诊断意义。方法：本文分组测定葡萄胎患者吸宫术前后血清β_2－MG值及其变化，以正常人、正常早孕、和早孕人流为对照组。结果：葡萄胎患者血清β_2-MG明显高于正常对照组和正常早孕组，具有显著性差异（P＜0．001）。结论：血清β_2-MG可为早期诊断葡萄胎提供依据。

Objective: To study the changes and diagnostic significance of serumbeta-2 microglobulin (β_2-MG) in the patients with grape mole. Methods: Serumβ_2-MG level was measured in patients with grop mole before and after artificialabortion. The control group inclued healths, normal early pregnancy and artificialabortion of early pregnancy. Results: The serum β_2-MG level in patients with grapemole was much higher than that in control group (P < 0. 001 ). Conclusions:Serum β_2-MG could be a useful parameter for early diagnosis of grape mole.