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小剂量阿立哌唑治疗恢复期精神分裂症病人嗜睡症状的疗效观察

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摘要 目的:观察小剂量阿立哌唑治疗恢复期精神分裂症病人的嗜睡症状的临床疗效。方法:对原用抗精神病药治疗的36例有嗜睡症状的恢复期精神分裂症病人,加用小剂量阿立哌唑,评定加药前后病人每天的睡眠时间。结果:加小剂量阿立哌唑后,睡眠时间明显减少(P<0.01)。结论:小剂量阿立哌唑治疗恢复期精神分裂症病人的嗜睡症状疗效明显。
出处 《温州医学院学报》 CAS 2008年第3期275-276,共2页 Journal of Wenzhou Medical College
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参考文献5

  • 1Zeman A, britton T, Douglas N,et al. Narcolepsy and excessive daytime sleepiness[J] BMJ,2004,329(7468):724-728.
  • 2Black J, Duntley SP, Bogan RK, et al. Recent advances in the treatment and management of excessive daytime sleepiness [J].CNS Spectr, 2007,12(2 Suppl 2): 1 - 14.
  • 3黄文武,姜德国.抗精神病新药阿立哌唑[J].上海精神医学,2003,15(5):307-308. 被引量:153
  • 4Roth T. Narcolepsy: treatment issues[J]. J Clin Psychiatry. 2007,68(Suppl 13): 16-19.
  • 5Miller DD.Atypical antipsychotics: sleep, sedation, and efficacy[J]. Prim Care Companion J Clin Psychiatry,2004, 6 (Suppl 2):3-7.

二级参考文献15

  • 1[1]Kikuchi T, Tottori K, Uwahodo Y, et al. 7-(4-[4-(2,3-Dichlorophenyl)-1-piperazinyl] butyloxy)-3,4-dihydro-2 ( 1H)-quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity. J Pharmacol Exp Ther, 1995 Jul, 274( 1 ) :329 ~ 336
  • 2[2]Fleishhacker WW. New developments in the pharmacotherapy of schizophrenia. J Neural transm Suppl, 2003, 105 ~ 117
  • 3[3]Oshiro Y, Sato S, Kurahashi N, et al. Novel antipsychotic agents with dopamine autoreceptor agonist properties: synthesis and pharmacology of 7-[ 4-( 4-phenyl-1-piperazinyl ) butoxy ]-3, 4-dthydro-2 (1H)-quinolinone derivatives. J Med Chem, 1998 Feb, 41 : 658 ~667
  • 4[4]Matsubayashi H, Amano T, Sasa M. Inhibition by aripiprazole of dopaminergic inputs to striatal neurons from substantia nigra. Psychopharmacolgy (Berl), 1999 Sep, 146(2) : 139 ~ 143
  • 5[5]Lawler CP, Prioleau C, Lewis MM, et al. Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes. Neuropschopharmacolgy, 1999 Jun, 20(6) : 612~627
  • 6[6]Inoue A, Seto M, Sugita S, et al. differential effects on D2 dopamine receptor and prolactin gene expression by haloperidol and aripiprazole in the rat ptiuitary. Brain Res Mol Brain Res, 1998 apr, 55 : 285 ~292
  • 7[7]Shapiro DA, Renock S, Arrington E, et al. Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology.Neuropsychopharmacology, 2003 May
  • 8[8]Jordan S, Koprivica V, Chen R, et al. The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT ( 1 A) receptor. Eur J Pharmacol, 2002 Apr 26,441(3) : 137 ~140
  • 9[9]Goodnick P J, Jerry JM. aripiprazole: profile on efficacy and safety.Expert Opin Pharmacother, 2002 Dec, 3(12) : 1773 ~ 1781
  • 10[10]Stahl SM. dopamine system stabilizers, aripiprazole, and the next generation of antipsychotics, part 1, "Goldilocks" actions at dopamine receptors. J Clin Psychiatry, 2001 Nov, 62 (11 ) : 841 ~ 842

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