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缬沙坦对老年高血压病患者阵发性心房颤动的作用 被引量:2

Effects of Vallartan on Paroxysmal Atrial Fibrillation in Eldly Patients with Hypertension
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摘要 目的:观察缬沙坦对老年高血压病患者阵发性心房颤动(简称房颤)的作用。方法:对本院114例高血压病患者分为常规治疗组和缬沙坦治疗组,观察两组治疗前后血压、动态心电图、心电图、心脏彩超和血生化的变化和房颤的发生情况。结果:与常规治疗组比较,缬沙坦治疗组房颤的发生率明显下降(P<0.05),ARB药物治疗对阵发性房颤起独立的影响作用。结论:老年高血压患者应用缬沙坦治疗,可使阵发性房颤的发生率明显下降。 Objective: To invest tigate the effects of Valsartan on paroxysmal atrial fibrillation in eldly patients with hypertension. Methods: One hundred and fourteen patients with hypertension were divided into routine therapy and Valsartan therapy. Blood pressure, ambulant ECG, Electrocardiogram, echocardiogram were all studied before treatment and after treatment. Results: Of those admitted, the number of atrial fibrillation in routime therapy were higher than in Valsartan group, (P〈0. 05), ARB therapy was associated with the rate of atrial fibrillation morbidity. Conclusion: Valsartan is associated with a decreased incidence of atrial fibrillation in patients with hypertension.
出处 《中国医药导刊》 2008年第1期97-97,99,共2页 Chinese Journal of Medicinal Guide
关键词 心房颤动 高血压病 缬沙坦 Atrial fibrillation Hypertension Valsartan
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参考文献3

  • 1Davies MD. Pomerance A. Pathology of atrial fibrillation in man. Br Heart J,1972;34:520-525
  • 2Corradi D, Callegari S. et al. Regional left atrial interstitial remodeling in patients with chronic atrial fibrillation undergoing mitral-valve surgery[J]. Virchows Arch, 2004;445 (5):498-505
  • 3Whchtell K, Lehto M, Gerdts E, et al. Angioten sin Ⅱ Receptor Blockade reduces New-on set Aerial Fibrillation and subsequent stroke compared to Aeenolol The Losartan Ineervention for En point Reduction in Hypertension (LIFE) stud [J]. J Am Coll Cardiol, 2005;45:712-719

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