冠心病患者调脂治疗间歇期血脂水平分析

Analysis of Blood Lipid Level of Coronary Heart Disease During the Statine was Discontinued

目的:探讨冠心病患者调脂治疗间歇期,血脂水平与冠状动脉病变的关系。方法:172例胸痛患者经冠状动脉造影分为对照组(31例);单支血管病变组(68例);双支血管病变组(53例);三支血管病变组(20例)。再根据患者的年龄、性别分为男性>60岁组(老年男性组52例);男性≤60岁组(38例);女性>60岁组(老年女性组36例);女性≤60岁组(15例)。分别将各组的血脂水平与对照组及低密度脂蛋白(LDL-c)达标值比较。结果:①与对照组比较,三支血管病变组、老年女性组胆固醇(TC)水平、LDL-c水平增高,有显著性差异(P<0.05,P<0.01)。②双支血管病变组与对照组比较,LDL-c水平无显著性差异(P>0.05),但LDL-c水平未达标。③与对照组比较,老年女性组中高密度脂蛋白(HDL)水平降低,有显著性差异(P<0.01);甘油三酯(TG)水平增高,有显著性差异(P<0.01)。结论:血脂异常仍然是冠心病二级预防中必需注意的重要危险因素之一。

Objective：To observe the relationship between the blood lipid level and severity of coronary arterial atherosclerosis of the patients with coronary heart disease （CHD） during the statine was discontinued. Methods： According to coronary, a total 172 borderline cases of C HD were divided into the control group（ 31 ） ;one-branch narrow vessel group（68 ） ;twobranch narrow vessel group（53 ） ;three-branch narrow vessel group （20）. Depends the age of the patients, the males were divided into two groups, 〉60（with 52 patients） ; ≤60（with 38 patients）. And the females were divided in the same way, 〉60 （ with 36 patients） ; ≤ 60 （ with 15 patients）. The blood lipid level of the three group and the patients of difference age and gender with CHD were analyzed. Results： The results showed. （1） The blood lipid levels of low-density lipoprotein cholesterol （LDL-c） and total cholesterol（TC） were higher in the three-branch narrow group and elderly male female patients with CHD groups than that eontrol（P 〈0. 05 ,P 〈0.01 ）. （2） LDL-c level were decreased to fall reached standard in two-branch narrow group. （3） The lipid level of high-density lipoprotein cholesterol （HDL-c） were much lower and triglyceride（ TG ） were higher in elderly female patients group than that control（ P 〈 0. 01 ）. Conclusion： Disorder of blood lipid level might be still one of the most important risk factors in secondary prevention of CHD.