干细胞移植与再生障碍性贫血治疗

Stem cell transplantation for treating aregenerative anemia

近30年来应用干细胞移植治疗重症再生障碍性贫血已取得了显著的临床进展,使再生障碍性贫血有了治愈的可能性。随着对患者预处理方案的逐渐改善,干细胞移植并发症的发生率及严重性均得到很好的控制。文章通过检索Pubmed数据库相关文献,了解干细胞移植治疗再生障碍性贫血的最新进展,揭示和探讨了干细胞移植预处理方案的改进对移植失败率的控制效果。

In recent 30 years, stem cell transplantation for severe aregenerative anemia has obtained significant clinical progress, so a regenerative anemia has the possibility of healing. With the improvement of pretreatment, the incidence and severity of complications after stem cell transplantation have been controlled. In this article, we retrieved relevant articles in Pubmed Database, and found the research progress of stem cell transplantation for treating aregenerative anemia. This article investigated the effect of pretreatment improvement on controlling failure rate of stem cell transplantation.