增殖诱导配体基因与消化系肿瘤

A Proliferation-inducing Ligand Gene and Digestive System Tumors

增殖诱导配体(aproliferation-inducing ligand,APRIL)基因是近年发现的肿瘤坏死因子超家族的新成员,研究发现APRIL基因在多种肿瘤组织,特别是消化道肿瘤中高表达,提示APRIL基因在肿瘤的发生、发展中发挥重要作用。对APRIL基因的深入研究将有助于进一步认识消化系肿瘤的本质,并为肿瘤的诊断和治疗提供新途径。

A proliferation-inducing ligand （APRIL） gene is a new member of tumor necrosis factor （TNF） superfamily discovered in recent years. Studies have shown that expression of APRIL gene is high in many tumor tissues, especially in digestive system tumors, which suggests that APRIL gene plays an important role in the development of tumors. Thus, further study on APRIL gene will be helpful to reveal the essence of digestive system tumors, and to provide new approaches for the diagnosis and treatment of these tumors.