摘要
目的:探讨顺铂联合香菇多糖治疗恶性胸腔积液的疗效及机制。方法:将74例恶性胸腔积液患者随机分为观察组(37例)和对照组(37例)。观察组37例患者放尽胸水后经胸腔内注入顺铂加香菇多糖进行治疗;对照组37例患者放尽胸水后经胸腔内注入顺铂进行治疗。结果:观察组有效率(86.5%)高于对照组(48.6%)具有显著性差异(P<0.05)。结论:顺铂联合香菇多糖治疗恶性胸腔积液患者有确切疗效。明显提高化疗药敏感性,提高患者生存期及生活质量。
Objective :To explore curative effect of cisplatin and lentinan on malignant pleural effusion.Method: 74 cases of patients with malignant pleural effusion were randomly divided into observataon group (37 cases) and control group (37 cases) . In observation group , 37 cases were intrathoracically injected with cisplatin and lentinan after pleural effusions were drained , and in the control , patients received cisplatin intrathoracicaUy only. Result: The response rate in observation group was 86.5 % , significantly higher than that of the control group (48.6%), P 〈 0. 05. Conclusion: Cisplatin and lentinan have confirmed effects on the patients with malignant pleural effusion.
出处
《河北医学》
CAS
2008年第6期636-637,共2页
Hebei Medicine
关键词
恶性胸腔积液
顺
铂
香菇多糖
Malignant pleural effusion
Cisplatin
Lentinan