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香菇多糖联合顺铂治疗恶性胸腔积液 被引量:11

Curative Effect of Cisplatin and Lentinan on Patients with Malignant Pleural Effusions
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摘要 目的:探讨顺铂联合香菇多糖治疗恶性胸腔积液的疗效及机制。方法:将74例恶性胸腔积液患者随机分为观察组(37例)和对照组(37例)。观察组37例患者放尽胸水后经胸腔内注入顺铂加香菇多糖进行治疗;对照组37例患者放尽胸水后经胸腔内注入顺铂进行治疗。结果:观察组有效率(86.5%)高于对照组(48.6%)具有显著性差异(P<0.05)。结论:顺铂联合香菇多糖治疗恶性胸腔积液患者有确切疗效。明显提高化疗药敏感性,提高患者生存期及生活质量。 Objective :To explore curative effect of cisplatin and lentinan on malignant pleural effusion.Method: 74 cases of patients with malignant pleural effusion were randomly divided into observataon group (37 cases) and control group (37 cases) . In observation group , 37 cases were intrathoracically injected with cisplatin and lentinan after pleural effusions were drained , and in the control , patients received cisplatin intrathoracicaUy only. Result: The response rate in observation group was 86.5 % , significantly higher than that of the control group (48.6%), P 〈 0. 05. Conclusion: Cisplatin and lentinan have confirmed effects on the patients with malignant pleural effusion.
作者 梁泳
出处 《河北医学》 CAS 2008年第6期636-637,共2页 Hebei Medicine
关键词 恶性胸腔积液 香菇多糖 Malignant pleural effusion Cisplatin Lentinan
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  • 1孙燕.全国肿瘤会议制定标准[J].中华肿瘤杂志,1980,2(2):150-153.
  • 2李振 许德顺 王化洲 等.恶性肿瘤的化学治疗与免疫治疗[M].北京:人民卫生出版社,1993.215.
  • 3仝运科 陈天法 等.顺铂加足叶乙甙联合化疗治疗恶性体腔积液[J].中华肿瘤杂志,1995,17(3):198-198.

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