2007年全国碘缺乏病实验室尿碘检测能力验证报告

Report of national proficiency testing for urinary iodine among the laboratories of Iodine Deficiency Disorders in 2007

目的考核各级尿碘实验室的检测能力及其持续性,了解各省实验室外质控网络的管理和运行情况。方法采用Z比评分法进行检测结果的统计学评价,Z分值的公议值来自所有参加实验室。结果参加考核的32个省级单位的尿碘实验室全部反馈了质控结果,并全部通过了能力验证,323个地市级尿碘实验室的反馈率为98.5%,合格率为95.4%;天津医科大学、中国疾病控制中心地病中心和越南的2个实验室通过了能力验证。结论全国省级实验室的检测结果非常接近,实验室内和实验室间变异很小,检测精密度和准确度均有明显提高,采用参考值和不确定度评价方法,其结果基本上与Z分值评价法相符;大部分地市级实验室的尿碘检测能力有了明显的提高;建议各级实验室要常规进行内部质量控制和常规使用标准物质。

Objective The proficiency testing was designed to understand the sustained performance ability of urinary io-dine labs at different levels and the operating situation of quality control network for iodine testing. Methods The testing results coming from the participatory labs were evaluated by using standard Z score generated from all the participatory labs. Results All 32 provincial participatory labs had qualifiedly fed back their testing results. At the prefecture level, the feedback rate was 98. 5% , and qualified rate was 95.4%. Conclusions The testing ability has been significantly improved through the operation of national quality control network and routine technical training. Inner Z score of provincial labs are distributed evenly. No obvious and systemic errors are found. It is suggested that internal quality control should be emphasized and reference materials should be routinely used in labs at different levels.