痛经模型建立和评价方法的思考

On building the dysmenorrhea model and assessment methods

原发性痛经是妇科常见病,因其发病率高及影响了人们的正常工作和日常生活而受到人们的关注。由于在人体研究痛经的发病机制和防治有许多因素限制,如观察组织病理生理的改变情况等,制备痛经模型显得尤为重要。本文对近20年痛经模型建立和评价的方法进行了系统回顾,以期为痛经病因、发病机制和防治等研究奠定基础。

Primary dysmenorrhea is a common disorder with a high incidence in women,which affects quality of work and life, and attracts attention. Since there are some limitations in study of human body on the trigger factors and prevention, such as the observation of physiopathologic changes in the tissue, it is essential to build the dysmenorrhea model. This article has systematically reviewed the building of dysmenorrhea model and assessment methods in the past 20 years. The purpose of the study is to lay a foundation for further research of the etiology, treatment and pre- vention of the disorder.