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小儿脑瘫的遗传学研究进展 被引量:5

Genetics research progress of cerebral palsy
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摘要 近年来脑瘫的病因在遗传、感染、早产等方面取得较大的进展。如基因位点的缺失、遗传性血栓的形成如Ⅴ因子Leiden突变、脑瘫患儿在数量上的性别差异、遗传多态性和早产/低出生体重关系、胎盘功能不足与胎儿宫内发育迟缓相关性、胎盘凋亡及凋亡相关基因等,从不同角度揭示遗传因素在脑性瘫痪发病中的作用。 The research on the etiology of cerebral palsy in many ways such as genetics, infection and premature delivery had made great progresses in recent years. Gene genetics such as genetic locus, gender different in number of cerebral palsy, genetic poly- morphism and premature delivery/low birth weight, placenta insufficiency and intrauterine growth retardation, apoptosis in the pla- centa and apoptosis - related genes had show the genetic factors in the invasion of cerebral palsy.
出处 《中国优生与遗传杂志》 2008年第6期4-6,共3页 Chinese Journal of Birth Health & Heredity
关键词 脑性瘫痪 病因学 遗传学 Cerebral palsy Etiology Genetics
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参考文献26

  • 1中华医学会儿科学分会神经学组.小儿脑性瘫痪的定义、诊断条件及分型[J].中华儿科杂志,2005,43(4):262-262. 被引量:1104
  • 2Raju TN. Historical perspectives on the etiology of cerebral palsy [ J ]. Clin Perinatol,2006,33 (2) :233 - 50.
  • 3Michael J Vincer, Alexander C Allen, K S Joseph, et al. Increasing Prevalence of cerebral palsy among very preterm infants : A Population -Based Study [J]. Pediatrics,2006,118(6) :1621 -1626.
  • 4Costeff H. Estimated frequency of genetic and nongenetic causes of congenital idiopathic cerebral palsy in west Sweden. Ann Hum [ J ]. Genet,2004,68(5) ,515 -520.
  • 5DP Mchale, AP Jackson, Campbell, et al. A gene for ataxic cerebral palsy maps to chromosome 9p12 -q12 [J]. Eur J Hum Genet,2000,8(4) : 267 -72.
  • 6Israela Lerer, Miehal Sagi, Vardiella Meiner, et al. Deletion of the ANKRD15 gene at 9p24.3 causes parent - of - origin - dependent inheritance of familial cerebral palsy [ J ]. Human Molecular Genetics, 2005,14(24) :3911 -20.
  • 7Kuroda MM, Weck ME, Sarwark JF, et al. Association of apolipoprotein E genotype and cerebral palsy in children [ J ]. Pediatrics,2007, 119(2) : 306 -13.
  • 8Hemminki K, Li X, Sundquist K, et al. High familial risks for cerebral palsy implicate partial heritable aetiology [ J ]. Paediatr Perinat Epidemiol,2007,21 (3) :235 -41.
  • 9Yehezkely - Schildkraut V, Kutai M, Hugeirat Y, et al. Thmmbophilia: a risk factor for cerebral palsy? [J]. Am J Med Genet A,2006, 140 (14) : 1504 - 10.
  • 10J L Halliday, D Reddihough, K Byron, et al. Hemiplegic cerebral palsy and the factor V Leiden mutation [ J ]. J Med Genet, 2000,37 ( 10 ) :787 - 9.

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