北京地区流动人口对出生缺陷发生率及检出率的影响

The effect of floating population on the incidence and detection rate of birth defect

目的探讨流动人口对出生缺陷发生率及检出率所产生的影响。方法10年发生出生缺陷的中期引产胎儿及围产儿的临床资料分两组,进行回顾性分析。结果前5年与后5年比较,1.出生缺陷总发生率分别为8.82‰及28.05‰;2.出生缺陷的顺位由神经管畸形变化为先天性心脏病;3.本市人口与流动人口出生缺陷的发生率分别为11.65‰、3.41‰(前5年)及18.17‰、37.10‰。结论1.10年来本市随流动人口的增加,出生缺陷的总发生率明显增加;2.出生缺陷前5年以神经管畸形为主,后5年则以先天性心脏病为主。

Objective ： To explore the effect of floating population on the incidence and detection rate of birth defect . Methods ： Retrospectively analyzing monitoring data in 1998 -2006 by descriptive statistic method according to previous five -year and later five - year. Results ： 1. The prevalence rate of birth defect in previous five - year and later five - year is8. 82‰及 28.05‰ respectively. 2. Congenital heart disease ranked in the first places among all birth defects and while neural tube malformation had declined. 3. The prevalence rate of birth defect is different between residence population and floating population , 11.65‰ vs 3.41‰ （previous five - year）, 18. 17‰vs37. 10‰ （later five -year） o Conclusion： The percentage of birth defect showed a upstrend in latest ten years accompanied with floating population increasing. Birth defects , with the highest incidence of congenital heart disease are primary cause of perinatal death.