摘要
可溶性白细胞分化抗原40配体作为急性冠脉综合征时血小板活化的指标,较肌钙蛋白而言,能提供动脉粥样斑块破裂和血小板激活的更为直接的信息。具有重要的早期诊断和预测意义。大量的研究已经证实了可溶性白细胞分化抗原40配体与急性冠脉综合征的密切关系。因此,临床上,将可溶性白细胞分化抗原40配体用于对急性冠脉综合征预后的预测与评估具有重要意义。本综述阐述可溶性白细胞分化抗原40配体的来源,可溶性白细胞分化抗原40配体与急性冠脉综合征关系,以及可溶性白细胞分化抗原40配体对急性冠脉综合征预后的预测价值。
Soluble CD40 ligand(sCD40L) which is the symbol of platelet activation has provided a more direct information of atherosclerotic plaque rupture and platelet activation as compared with cardiac troponin. So it has an important value in the prognosis of acute coronary syndrome(ACS). There are a large number of investigations that have indicated the relations between sCD40L and ACS. Therefore, sCD40L can be used in the evaluation of prognosis of acute coronary syndrome. This review expounds it' s origin, the relation with ACS and the value of evaluation in acute coronary syndrome.
出处
《心血管病学进展》
CAS
2008年第B05期36-38,共3页
Advances in Cardiovascular Diseases