摘要
目的分析梭形细胞型脂肪肉瘤的临床病理特点、诊断及鉴别诊断。方法对2例梭形细胞型脂肪肉瘤进行HE染色、免疫组织化学检测并分析病理学特征。结果肿瘤镜下排列成旋涡状或束状，一些成熟的脂肪细胞中散在大小不一的异型细胞；免疫组织化学结果显示梭形细胞Vimentin阳性，S-100、MSA部分阳性，MBP、HMB45、Desmin阴性，脂肪细胞及核深染的异型细胞呈S-100阳性。结论梭形细胞型脂肪肉瘤是一种少见软组织恶性肿瘤，需与多种软组织肿瘤鉴别。
Objective To inyestigate the clinicopathological characteristics of Spindle cell liposarcoma and its main characteristics for diagnosis. Methods HE dyeing, immunohistochemistry checks and pathological feature analysis were carried out on a cases of Spindle cell liposarcoma. Results Microscopically, the tumor often occurred as nerves spindle cell align like vortex or sarciniform. Some ripe adipose cells scattered in a few atypia cells with trachychromatic nuclear. Immunohistochemically, the spindle cells were positive for Vimentin and part of Spindle cells were positive for S - 100 and MSA, whereas MBP, HMB45, Desmin. Adipose cells and atypia cells were positive for S - 100. Conclusion Spindle cell liposarcoma is an extremely rare malignant tumor, and the prognosis is fine. It is necessary to differentiate from soft tissue neoplasms.
