壳聚糖及其衍生物固载环糊精的制备及应用研究进展

Research progress of preparation and application of cyclodextrin immobilized chitosan and its derivatives

壳聚糖固载化环糊精是一类新型的功能高分子材料,它既具有环糊精的包络识别、控释和运输性能,又具有壳聚糖良好的生物相容性、无毒性和生物降解性能等特性,可用作药物控制释放载体、色谱分离填料和水处理剂等。简要综述了近几年壳聚糖固载化环糊精的方法及其应用研究进展。

Cyclodextrin immobilized chitosan is a kind of novel functional macromolecule that possesses the cumulative effects of inclusion, size specificity, controlled release ability and transport properties of cyclodextrin as well as the biocompatibility, non-toxicity, and biodegradatibility of chitosan. It can be used in many types of applications, such as delivering drugs, treatment of waste water and chromatographic support. This paper reviewes the recent study on different methods of cyclodextrin grafting onto chitosan or its derivatives and discusses its applications.