湛江市板齿鼠对杀鼠灵的敏感性调查

The susceptibility of Bandicota indica to Warfarin in Zhanjiang

目的了解湛江市板齿鼠对杀鼠灵的敏感性变化，提供科学灭鼠用药依据。方法在实验室做无选择性摄食试验。将试鼠雌雄分开，随机分组，按5个不同食毒期摄食0．002％杀鼠灵毒饵。用Bliss计算机程序，计算不同食毒期与对应死亡率之间的关系。结果板齿鼠性别之间对杀鼠灵的敏感性差异无统计学意义（R〉0．05，P〉0．05），故将雌雄数据合并计算，得毒力回归方程Y=4．25＋2．57x，LFP50、LFP99及其95％置信限分别为1．95（1．48＋2．58）d和15．71（6．29～39．23）d。结论与1987年的实验室敏感性本底测定结果比较，虽然湛江市板齿鼠对杀鼠灵耐受能力强的个体比例有所增加，但总体对药物还是敏感的，只要保证毒饵的配制质量，提高毒饵的适口性，第一代抗凝血灭鼠剂还可继续用于毒杀板齿鼠。

Objective To understand susceptibility change of Bandicota indica in Zhanjiang to Warfarin, providing scientific basis for well-organized deratization. Methods The males and females were firstly separated by sex and then divided into groups at random. No-choice tests were carried out using the Warfarin bait at concentration of 0. 002% at five different feeding days. The relationships between death rates and the different feeding days were analyzed by Bliss software. Results For the susceptibility to Warfarin, there was no significant difference （Pb 〉0.05, PLFP50 〉0.05） between males and females. Calculated based on these data, the LF-P line was y ： 4.25 ＋ 2.57x, and LFPs0, LFP99 and its 95% confidence limits for Bandicota indica were 1.95（1.48-2.58）d and 15.71 （6.29-39.23）d, respectively. Conclusion Comparing with the susceptibility results detected in 1989, the local Bandicota indica was still sensitive to anticoagulant rodenticides though the proportion of high tolerant individual increased. The rodenticide could be continued to kill Bandicota indica as long as the quality of the poison bait was assured and the palatability was enhanced.