304例鼻咽癌患者治疗后质量校正生命年调查

Quality-adjusted life year in 304 treated nasopharyngeal carcinoma patients

为了评价鼻咽癌治疗后患者的质量校正生命年（QALY）及其影响因素，采用华盛顿大学生存质量量表对304例鼻咽癌随访患者进行调查，计算QALY，选出其影响因素。随访时间、年龄与QALY呈负相关，生存质量得分与之呈正相关，无复发、N分期越早，QALY值越高。QALY考虑了生存质量的损失和生存时间长短，是评价鼻咽癌患者疾病负担的有效指标。

To evaluate quality-adjusted life year （QALY） and relevant impact factors in 304 patients with nasopharyngeal carcinoma （NPC）, post-radiotherapeutic subjects were surveyed by means of questionnaire and simplified Washington University-quality of life （UW-QOL）. QALYs were calculated and impact factors were identified. Duration of follow-up and age were negatively correlated with QALY. Patients at lower N stage had increased QALY. Decreased QALY was found in recurrent patients. Due to coconsideration to the lost quality of life and survival, QALY could serve as an effective method to evaluate the burden of disease in NPC patients.