用放射性受体结合分析法研究补肾填精中药对老年大鼠脑组织中神经递质受体的影响

Research on effect of Traditional Chinese Medicine of tonifying the shen and the deficient essence on neurotransmitter receptor of senile rats by radio-ligand binding assay

用放射性受体结合分析法研究了补肾填精中药对雌、雄性老年大鼠脑组织中神经递质受体的影响。实验表明:雌、雄性老年大鼠大脑皮层组织中α_1和DA(多巴胺)受体的结合容量(R_1)有不同程度降低,补肾填精中药固真冲剂可明显增加老年大鼠大脑皮层组织中α_1和DA受体的R_1值,这一作用被认为可能对脑组织产生延缓衰老的作用。

Experiments showed that Rt of a1 and DA receptors decreased in cerebral cortox of senile rats as compared with young rats. But for the senile rats taking the Traditional Chinese Medicine Guzhen recipes for 4 months the above Rt values were obviously increased, which implied that the recipe had some function of delaying cerebral senility.