蒙药草乌药效组分的电喷雾质谱研究

Study on bioactive components of Aconitum kusnezoffii Reichb. by ESI-MSn

目的:分析传统蒙药草乌的药效组分。方法:利用电喷雾串联质谱(ESI-MS)对蒙药草乌的水煎煮液进行了直接分析。结果:草乌水煎煮液中含有单酯型、双酯型和脂类等共3种类型生物碱。结论:利用电喷雾质谱技术,可以对蒙药草乌药效组分作出快速分析,方法简便,直观,用样量少。

Objective： To analyze the bioactive components of Acnoitum Kusnezoffii Reichb..Methods： To detect the water extraction of Aconitum kusnezoffii Reichb.by the method of ESI-MSn.Results： Three kinds of alkaloids were detected in the water extraction of Aconitum kusnezoffii Reichb.：monoester alkaloids,diester-diterpenoid aconitines and lipo-alkaloids.Conclusion： The effect components of processed and unprocessed Acnoitum Kusnezoffii Reichb.can be analyze rapidly by ESI-MSn,and only needs few sample.