沐舒坦雾化吸入预防食管癌术后肺部并发症的临床观察

The clinical observation on Mucosolvin atomization preventing lung complication after esophageal carcinoma surgery

目的探讨食管癌术后患者应用沐舒坦雾化吸入预防肺部并发症的临床效果。方法将122例食管癌手术患者按入院日期单双号随机分组法分为两组，观察组62例和对照组60例，观察组应用沐舒坦超声雾化吸入，对照组采用传统超声雾化吸入，对比分析两组患者的肺不张及肺炎的发生率，并经统计学处理。结果两组患者的肺不张、肺炎发生率分别经统计学处理，有显著性差异，P〈0．001。说明食管癌术后患者采用沐舒坦超声雾化有效地降低患者肺部感染率。结论沐舒坦超声雾化能将药液直接作用于气道，可减少气道黏膜滞留、促进排痰、改善呼吸功能的作用。沐舒坦超声雾化明显优于传统超声雾化法。

Objective Study the clinical efficacy with Mucosolvin atomization preventing lung complication after esophageal carcinoma surgery. Methods 122 esophageal cancer patients were randomly divided into two groups by the date of admission. The observation group was 62 cases and the control group was 60 cases. The observation group was treated by Mucosolvin ultrasonic atomizing inhalation, the control group was treated by traditional ultrasonic atomizing inhalation, contrast analyzed the incidence rate of pulmonary atelectasis and pneumonic in both group, then did the statistical treatment. Results There is significant difference in the incidence rate of pulmonary atelectasis and pneumonic between two groups, P 〈0. 001. It demonstrated that Mucosolvin ultrasonic atomizing inhalation can effectually reduced pulmonary infection rate in the post - surgery esophageal cancer patient. Conclusion The Mucosolvin ultrasonic atomizing can make the drug directly effect on the airway, decrease the stagnation of airway, promote to eject the sputum, improve the respiratory function. The Mucosolvin ultrasonic atomizing is obviously better than the traditional ultrasonic atomizing.