γ射线慢性照射对急性照射诱发兔外周血染色体畸变、微核和淋转率的影响

Influence of chronicγ-ray radiation on chromosome aberration,micronucleus and transformation frequency in peripheral blood lymphocytes in rabbits induced by acute radiation

本文研究了γ线慢性照射对急性照射诱发兔外周血染色体畸变、微核和淋巴细胞转化率的影响。结果表明,先给家兔以0.26mGy/min(0.05Gy/d)的γ线连续照射20天(累积剂量1.0Gy后,立即以0.25Gy/min的γ线急性照射2.0Gy,其所诱发的外周血淋巴细胞染色体畸变率、微核率与单纯急性照射组比较明显减低,而淋巴细胞转化率却明显增高。

In this paper, influence of chronic γ-ray radiation on chromosome aberration, mi-cronucleus and transformation frequency in peripheral blood lymphocytes in rabbits induced by acute radiation was described. The result indicated that after rabbits were irradiated continuously by γ-ray at 0.26 mGy/min(0.05Gy/d) for 20 days (accumulation dose 1.0Gy), and immediatly acutely irradiated to 2.0 Gy (at 0.25Gy/min), the chromosome aberration frequency and micronucleus frequency in peripheral blood lymphocytes significantly decreased and lymphocyte transformation frequency significantly increased in comparison with acute radiation control group.