3-Quinuclidone中间体的合成

Synthesis of 3-Quinuclidone intermediate

3-奎宁环酮可用于合成3位取代的奎宁环化合物、氨基苄胺化合物、奎宁环基甲酰胺类化合物等药物中间体。本文设计了一种3-奎宁环酮新的合成方法,并做了初步的实验研究,制备了3-奎宁环酮的中间体,为整个合成路线的完成奠定了基础。

3-quinuclidone can be used to synthesize pharmic intermediate like 3-substituted quinuclidines, seeaminoben Zylamines, quinuclidinyl benzamides and so on. We have designed a practical synthesis of 3-quinuclidone and synthesized some intermediates, that laid a foundation for the completion of the synthesis of 3-quinuclidone.