河北省2006年麻疹实验室监测结果分析

Analyses of laboratory surveillance results for measles in 2006 in Hebei Province

目的:为了控制和消除麻疹,进一步提高实验室监测工作质量。方法:麻疹IgM和IgG测定用ELISA方法,病原学检测按WHO推荐方法进行。结果:河北省2006年麻疹实验室检测血清标本7395人份,麻疹IgM抗体阳性4419例,阳性率59.76%;麻疹IgM抗体阴性血清标本检测风疹IgM抗体2622例,阳性291例,阳性率11.10%。2006年167人份咽拭子标本中分离出30株麻疹病毒,经核苷酸序列分析鉴定,全部为H1 a基因型。结论:实验室监测是麻疹监测系统的重要组成部分,对消除麻疹和控制风疹工作发挥着重要作用。河北省目前流行的麻疹野病毒为H1基因型,以散发为主,人群免疫力水平较高。

Objective：To control and eliminate measles and further promote the quality of measles surveillance.Methods：The IgM and IgG of measles were tested with ELISA,and measles viruses were isolated according to the recommendatory method of WHO.Results：The 4419 of 7395 serum samples in 2006 measles lab.in Hebei province were Ig M positive for measles,and its positive rate was 59.76%.There were 291 Ig M positive for Rubella in 2622 Ig M negative samples for measles,and its positive rate was 11.10%.30 Measles viruses were isolated from 167 throat swabs,and their sequence analyses indicated that all of them were of H1a genotype.Conclusion：Laboratory surveillance is the significant part in measles surveillance system,and plays a very important role in measles elimination and Rubella control.At present,epidemic wild-viruses of measles in Hebei Province are H1 getotype with main sporadic and the higher level of immunity among population.