端粒与Sheherin复合体
摘要
端粒是真核细胞线性染色体的末端结构,由简单的DNA串联重复序列和一系列相关的蛋白质组成,在染色体末端形成一个“帽状”结构,对染色体起重要的保护作用,防止出现染色体的断裂、降解与末端融合,与细胞分化、组织再生、DNA修复、细胞的衰老和死亡,以及恶性肿瘤的发生都有着密切的关系。
出处
《中华病理学杂志》
CAS
CSCD
北大核心
2008年第6期410-412,共3页
Chinese Journal of Pathology
基金
国家自然科学基金资助项目(30470796)
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