潍坊地区外阴阴道假丝酵母菌病相关危险因素研究

Study on the risk factors of vulvovaginal candidiasis

目的:探讨外阴阴道假丝酵母菌病(vulvovaginalcandidiasis,VVC)的相关危险因素。方法:采用1∶1病例-对照研究设计,对200例真菌培养阳性的VVC患者及200例真菌培养阴性者或真菌培养阳性无症状的带菌者进行问卷调查,用Logistic回归分析方法筛选主要危险因素,并评估它们在VVC发病中的相对重要性。结果:Logistic回归分析提示非经期用护垫、VVC病史、口交、阴道冲洗、避孕套、近1个月应用抗生素、心情抑郁、口服避孕药、糖尿病等在VVC发病因素中具有统计学意义,且对VVC发病的相对影响依次减弱。结论:Logistic回归分析提示在VVC发病中具有统计学意义的因素,可能是外阴阴道假丝酵母菌病危险因素。

Objective： To explore the main risk factors of vulvovaginal candidiasis. Methods：Two hundred patients with positive-culture for candida and two hundred control cases with negative-culture for candida were chosen to fill questionnaire. Then the risk factors were selected by Logistic stepwise regression and the relative importance among them was evaluated. Results： Protective pad used during non-menstruation, VVC history, oral sexual habits, vaginal irrigation, condom, systemic broad-spectrum antibiotics, mood depression, oral contraception, diabetes were found with statistical significance, which attenuated in order. Conclusion：The selceting WC risk factors by logistic stepwise regression my be the risk factors associated with VVC.