液基细胞学检查在诊断宫颈病变中的临床应用

The Clinical Application of Thinprep Liquid-based Cytology Test in the Diagnosis of Cervical Lesions

目的探讨液基细胞学配合阴道镜检查对诊断宫颈病变的临床价值。方法2006年1～7月,对2200例患者进行液基细胞学检查,对其中34例细胞学提示阳性者行阴道镜下活组织病理检查,细胞学诊断采用TBS分段系统。结果共检出阳性涂片34例,占1.54%,其中不典型鳞状细胞18例,占0.81%;低度鳞状上皮内瘤变9例,占0.41%;高度鳞状上皮内瘤变6例,占0.12%;鳞状上皮癌0例,腺癌0例。与阴道镜下活组织病理诊断符合率分别为LSIL94.4%,HSIL100%。结论生育年龄段(20～50岁)的妇女,应定期进行液基细胞学检查,可早期发现宫颈病变,细胞学阳性者应配合阴道检查及镜下活检病理诊断,以便进一步明确诊断,早期治疗。

Objective To evaluate the clinical value of thinprep liquid-based cytology test （TCT） combined with colposcopy in the diagnosis of cervical lesions. Methods 2200 cases of patients were detected by Thinprep liquid-based cytology from January to July 2006. The diagnosis criteria were hased on the Bethesda system（TBS）. And 34 positive cases were examined by colposcope. Results A total of 34 cases were positive smear, or 1.54 %, of which does not atypical squamous cells（ASCUS） 18 cases,accounting for 0.81% ;low squamous intrae ithelial neoplasia（LSIL） 9 cases, accounting for 0.41% ; highly scales-intraepithelial neoplasia （HSIL） 6 cases, accounting for 0.12% ; squamous cell carcinoma （SCC） 0 case, adenocarcinoma （AC）0 case. Colposcopy and biopsy diagnosis rates were LSIL 94.4%,HSIL 100%. Conclusion Women of child-hearing age（20 - 50）should be conducted on a regular Thinprep liquid-based cytology,which is early detection of cervical lesions. Positive cytology should be in line with vaginal examination of biopsy and pathological diagnosis,in order to further clarify the diagnosis and early treatment.