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体外循环冠脉搭桥术患者围术期炎性细胞及细胞因子浓度变化 被引量:1

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摘要 目的观察体外循环冠脉搭桥术患者围术期血清炎性细胞及细胞因子浓度变化特征。方法选择近期在我院住院接受CPB冠脉搭桥术治疗患者51例,40例同期非体外循环冠脉搭桥术患者为对照组,入选对象手术前、手术后即刻、手术后4h、手术后24h接受了血清炎性细胞及细胞因子浓度检测。结果两组患者手术前各炎性细胞及细胞因子浓度测定值分布接近(P均>0.05),手术后即刻开始两组白细胞总数、中性计数、细胞因子IL-6和IL-8均明显增加,手术后4h为最高值,手术后24h时各指标测定值开始下降。与对照组比较,CPB组升高更显著,其中手术后各时间段大多数测定值明显高于对照组(P均<0.01~0.05)。结论CPB冠脉搭桥术患者手术后早期炎症反应更明显。
作者 李春晖
出处 《中国现代医生》 2008年第15期154-155,共2页 China Modern Doctor
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