摘要
应用矽宁对小鼠进行了骨髓细胞微核试验、精子畸形试验及姊妹染色单体互换试验,结果显示:矽宁能引起小鼠骨髓嗜多染红细胞微核率和精子畸形率升高,但不存在剂量-反应关系,对小鼠姊妹染色单体交换频率(SCE)无影响。
The hereditary toxicity of Xinin on mice was observed by sperm deformity test,marrow micronucleus test and sister chromatid exchange. The results showed that Xinin could make the rateof spermatic deformity and marrow cells micronucleus in mouse increase significantly, however,there existed on dose-response relationship. Also Xinin had no effect in the frequencies of sisterchromatid exchanges.
出处
《工业卫生与职业病》
CAS
CSCD
1997年第6期332-334,共3页
Industrial Health and Occupational Diseases
关键词
矽宁
微核
精子畸形
染色单体互换
Xinin
Micronucleus
Sperm deformity Sister chromatid exchange