摘要
目的:观察法莫替丁与左旋米唑联用对复发性口腔溃疡的疗效。方法:复发性口腔溃疡病人100例,随机均分为法莫替丁组(男性22例,女性28例,年龄24±s8a)与甲硝唑组(男性24例,女性26例,年龄25±9a),法莫替丁组给法莫替丁20mg,po,bid,左旋米唑25mg,po,tid,局部外涂法莫替丁粉,tid;甲硝唑组给甲硝唑0.4g,维生素C0.2g,维生素B210mg,po,tid,局部外涂金霉素甘油,tid,疗程均为1wk。结果:法莫替丁组总有效率(100%),高于甲硝唑组(82%)(P<0.01);复发率低于对照组(P<0.05或0.01)。结论:法莫替丁与左旋米唑联合治疗复发性口腔溃疡疗效满意。
AIM: To observe the therapeutic effect of famotidine plus levamisole in treating recurrent aphthous ulceration (RAU). METHODS: One hundred patients with RAU were divided randomly into 2 groups: the experimental group (M 22, F 28; age 24±s 8 a) and the control group (M 24, F 26; age 25±9 a). The patients in the experimental group were given famotidine 20 mg, po, bid, levamisole 25 mg, po, tid, and famotidine powder smeared on the surface of ulceration. The patients in the control group were given metronidazole 400 mg, ascorbic acid 200 mg, riboflavin 10 mg, po[WTBZ], tid and chlortetracycline glycerol smeared on the surface of the ulceration. The therapy courses of both groups were 1 wk. RESULTS: The marked and total effective rates of the experimental group were higher than those of the control group and the relapse rate of the experimental group were lower than that of the control group (P<0.01 or 0.05). CONCLUSION: The therapeutic effect of famotidine plus levamisole is satisfactory in treating recurrent aphthous ulceration.
出处
《新药与临床》
CSCD
北大核心
1997年第6期339-341,共3页
关键词
口疮性
口炎
法莫替丁
左旋米唑
aphthous stomatitis
famotidine
levamisole
metronidazole