急性心肌梗死急诊经皮冠状动脉介入治疗的近期疗效观察

In-hospital effect of emergency percutaneous coronary intervention on patients with acute myocardial infarction

目的评价急诊经皮冠状动脉介入(PCI)治疗急性ST段抬高型心肌梗死(STEMI)的近期疗效。方法109例STEMI患者行急诊PCI治疗(PCI组),并与178例同期接受尿激酶静脉溶栓的STEMI患者(UK组)进行住院期间疗效比较。结果与同期溶栓治疗相比,急诊PCI胸痛缓解迅速,120minST段回落明显,再灌注成功率高(P<0.01);住院期间梗死后心绞痛(P<0.01)、再梗死及死亡率明显降低(P<0.05);严重并发症发生率无明显增加。结论急诊PCI是急性心肌梗死(AMI)安全有效的治疗方法,并可进一步降低死亡率。

Objective To evaluate the effect of emergency percutaneous coronary intervention （PCI） on patients with acute ST segment elevated myocardial infarction （STEMI）. Methods 109 cases of STEMI underwent emergency PCI （PCI group） and 178 cases underwent thrombolytic therapy with urokinase （UK group） were enrolled, In-hospital effects were compared between the two groups. Results Compared with UK group,the chest pain relief, 120 min ST segment reduction and achievement ratio of reperfusion were more significant in PCI group （P〈0.01） ,angina of post AMI（P〈0.01 ）,recurrent MI,in-hospital mortality （P〈0.05） in PCI group were markedly decreased. Conclusion Emergency PCI is safe and efficient, and can reduce in-hospital mortality.