期刊文献+

肾移植术后重症肺炎诊治体会 被引量:2

下载PDF
导出
摘要 【目的】探讨肾移植术后重症肺炎的临床特点和治疗方法。【方法】回顾分析14例肾移植术后重症肺炎患者临床资料,感染均发生在肾移植术后3-6月,免疫抑制剂量偏大,主诉为呼吸急促、胸闷,发热;生化检测示血浆白蛋白下降明显,血气分析均为低氧,低C02血症,氧饱和度进行性下降。胸片示肺部广泛渗出,实变阴影。治疗方法包括:停用抗排异药物、早期使用小剂量甲基强的松龙(MP)、联合抗病毒、抗细菌及抗真菌治疗及氧疗。【结果】14例患者治愈10例,好转1例,死亡3例。治疗期间肾功能均正常。【结论】肾移植术后免疫抑制过度是并发重症肺炎的高危因素;重视体温监测,活动后气促及不明原因血清白蛋白下降有助于早期诊断;果断停用抗排异药物,联合抗病原治疗,早期使用MP及恰当氧疗是治疗成功的关键。
出处 《医学临床研究》 CAS 2008年第5期895-897,共3页 Journal of Clinical Research
  • 相关文献

参考文献7

二级参考文献38

  • 1Wslsh RF , Springate JE , Spivack BS , et al .Cyclosporine and adult respiratory distress syndrome. Transplantation, 1988, 46:776-777.
  • 2Shorr AF, Abbott KC, Agadoa LY. Acute respiratory distress syndrome after kidney transplantation: epidemiology, risk factors,and outcomes. Crit Care Med, 2003,31 : 1325-1330.
  • 3Patel R,Snydman D,Rubin R,et al.Direct detection of cytomegalovirus in peripheral blood leukocyte:a review of the antigenemia assay and polymerase chain reaction.Transplantation,1992,54:193-198.
  • 4Yang CW,Kim YO,Kim YS,et al.Clinical course of cytomegalovirus with and without ganeiclovir treatment in CMV-seropositive kidney transplant recipients.Am J Nephrol,1998,18:373-378.
  • 5Sarmieto TM, Dockrell DH, Schwab TR, et al. Mycophenolate mofetil increases cytomegalovirus invasive organ disease in renal transplant patients[J]. Clin Transplant, 2000, 14:136-138.
  • 6Anglicheau D, Lautrette A, Scieux C, et al. Lowering immunosuppression is safe and effective to treat altered pattern of CMV infection in renal transplant recipients on valciclovir prophylaxis[J]. Transplant Proc, 2002,34 (7): 2826-2827.
  • 7Shorr AF, Susla GM, Pharm D, et al. Pulmonary infiltrates in the non-HIV-infected immunocompromised patient: etiologies, diagnostic strategies, and outcomes[J]. Chest, 2004,125:260-271.
  • 8Linhares MM, Gonzalez AM, Trivino TV, et al. Simultaneous pancreas-kidney transplantation: infectious complications and microbiological aspects[J]. Transplant Proc,2004,36: 980-981.
  • 9Tveit DJ, Hypolite IO, Poropatich RK, et al. Hospitalizations for bacterial pneumonia after renal transplantation in the United States[J]. J Nephrol, 2002,15(3):255-262.
  • 10Durlik M. Comparison of antigenemia (pp65) assay and polymerase chain reaction in diagnosis of cytomegalovirus infection in renal transplant recipients treated with ATG[J]. Transplant Proc, 2000, 32(6): 1350-1352.

共引文献168

同被引文献28

引证文献2

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部