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异丙酚麻醉状态下拔除气管导管 被引量:1

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摘要 目的比较异丙酚与异氟醚麻醉状态下拔除气管导管的优劣。方法将择期腹腔镜胆囊切除术患者60例随机分成异丙酚组(P组,n=30)和异氟醚组(I组,n=30)。P组在胆囊切除后,关闭异氟醚蒸发罐并给予异丙酚4 mg.kg-1.h-1静脉泵维持;I组在胆囊取出腹腔后,关闭异氟醚蒸发罐并将呼气末异氟醚浓度(EtISO)维持在0.5%。观察两组入室后、手术结束时、气管拔管前、气管拔管后和气管拔管后5 min各时段的心率(HR)、收缩压(SBP)、舒张压(DBP)、血氧饱和度(SPO2)、呼气末二氧化碳(PETCO2)和EtISO,以及拔管时间、睁眼时间、定向力时间,围拔管期的无意识躁动、恶心和呕吐情况。结果手术结束时和气管拔管前的EtISO P组[(0.39±0.10)%、(0.13±0.06)%]低于I组[(0.52±0.14)%、(0.20±0.06)%](均P<0.01);拔管、睁眼和定向力时间P组[(9.23±3.86)min、(12.33±3.75)min和(16.67±3.48)min]短于I组[(12.83±4.61)min(P<0.05)、(16.57±4.17)min和(20.70±4.47)min(均P<0.01)]。P组患者未发生无意识躁动,I组发生4例;两组均无恶心呕吐。结论异丙酚用于麻醉状态下拔除气管导管,能使麻醉恢复过程安全舒适,在防止围拔管期的无意识躁动和缩短麻醉恢复时间方面优于异氟醚。
出处 《现代医学》 2008年第1期55-57,共3页 Modern Medical Journal
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