胰腺实性假乳头状瘤诊治分析

Solid-pseudopapillary tumor of pancreas: diagnosis and treatment

目的探讨胰腺实性假乳头状瘤的临床病理学特点和治疗方法。方法回顾性分析2004年～2007年收治的15例胰腺实性假乳头状瘤的临床资料。结果15例患者中。男1例,女14例;年龄10～71岁,平均(30.1±13.9)岁。肿瘤位于胰头5例,胰颈体部5例,胰尾5例。3例患者行胰十二指肠切除术,5例患者行肿物局部切除术,6例患者行胰体尾、脾联合切除术,腹腔镜胰体尾切除1例。肿瘤直径平均(6.5±3.2)cm。术后1例患者发生胰瘘。对13例患者进行随访,平均随访时间32个月,无死亡病例。结论胰腺实性假乳头状瘤是少见、好发于青年女性的低度恶性肿瘤。应积极的手术切除,预后良好。

[Objective] To investigate clinicopathological features and treatment of solid-pseudopapillary tumors of pancreas. [Methods] A serie of 15 patients admitted from 2004 to 2007 with solid-pseudopapillary tumors of pancreas were retrospectively reviewed. [Results] Mean age of the 15 patients was （30.1±13.9） years （range from 10-71）. Including 1 man and 14 women. The lesions were located in the head of pancreas in 5 patients,in the body and neck in 5, and in the tail in 5. Surgical procedures included pancreaticoduodenectomies in 3 patients, simple enucleation in 5, distal pancreatectomy with splenectomy in 6, and 1 laparoscopic distal pancreatectomy. The mean tumor size was （6.5±3.2） cm. Pancreatic fistula occurred in 1 patient. The mean follow-up period was 32 months, and all patients were alive. [Conclusion] Solid-pseudopapillary tumor of pancreas was a kind of rare tumor with low malignant potential that predominantly found in young women. Favorable prognosis may achieve after complete surgical excision.