摘要
报道大蒜精对动物血脂的影响及急性毒性作用。结果显示:大蒜精0.5g/kg、1g/kg,po14d,既可防止高脂血症大鼠TC、TG的升高及HDL—C的降低,又可降低高脂血症大鼠的TC、TG及升高HDL-C水平。但大蒜精0.5g/kg,1.2g/kgPO,14d对正常大鼠血脂水平无明显影响。大蒜精灌胃给药的能耐受量为31.259/kg。提示大蒜精对大鼠高脂血症有防治与治疗作用且毒性甚微。
This article reported the influence of Garlic Essence on blood-fat of animal and its acute toxicity. As a result,Garlic Essence (0. 5, lg/kg,po 14d) could not only prevent the raising of TC and TG,and decreasing of HDL-C of rats fed with high fat forage,but also decrease TC and TG,and raise HDL-C level of rats with hyperlipemia symptom. But it (0.5, 1,2g/kg,po 14d) showed no significant effect on normal blood-fat level of rats. Its tolerance dose was 31.25g/kg when it was taken in stomach perfusion,which suggested that it have prevention andtherapy actions on hyperlipemia symptom of rat,and little toxicity.
出处
《中成药》
CAS
CSCD
1997年第12期30-31,共2页
Chinese Traditional Patent Medicine