Bricasol气雾剂治疗支气管哮喘临床及即时肺功能研究

The study of the treatment for bronchial asthma with Bricasol aerosol

目的研究应用Bricasol气雾剂后肺功能的改善情况及治疗效果。方法选择支气管哮喘发作期患者32例,其中男16例,女16例,分男、女两组观察。患者到实验室后先休息10～15min,然后吸入Bricasol气雾剂共两喷,间隔半分钟,剂量共0.5mg,观察治疗前和治疗后1、5、15min的肺功能变化。结果男、女两组吸药后1、5、15minFEV1.0均值;V75吸药后5、15min均值;PEFR女吸药后1、5、15min、男吸药后5、15min均值;FVC女吸药后1、5、15min均值均较吸药前明显增加或极明显增加。所有观察对象均于吸药后5min憋喘症状明显减轻,听诊哮鸣音减少,15min憋喘症状改善最为明显。结论吸入Bricasol气雾剂后,支气管哮喘患者肺功能明显改善,显效迅速,疗效好,是较理想的支气管舒张剂。

Objective To study therapeutic efficacy and change of pulmonary function of the treatment for bronchial asthma with Bricasol aerosol. Methods There were 32 patients in periods of onset of bronchial asthma. 16 were male, the rest 16 were female. Patients breathed in 2 spray of Brlcasol aerosol （0. 5 mg） after taking a rest of 10-15 minutes,each spray had a interval of 0.5 minutes. Then to observe the change of pulmonary function of pre-treatment and 1 minutes and 5 minutes and 15 minutes post-treatment. Results The FEV1.0 of 1 minutes,5 minutes, 15 minutes post-treatment and V75 of 5 minutes, 15 minutes post-treatment increase significantly than that pre-treatment of the male and female groups. The PEFR of 1 minutes,5 minutes, 15 minutes post-treatment of female group and 5 minutes, 15 minutes post-treatment of male group increased significant than that pre-treatment. The FVC of 1 minutes ,5 minutes, 15 minutes post-treatment of female group increased significant than that pro-treatment. The symptom of wheeze of all the patients had significant relieve,and the wheezing rale decreased significant with stethoscopy. The symptom of wheeze got the most relieve at 15 minutes post-treatment. Conclusion The pulmonary function of patient with bronchial asthma increased significant after treatment with Bricasol aerosol. The therapeutic efficacy is good and rapid. The Bricasol aerosol is the ideal bronchodilators.