食管癌淋巴结微转移检查

DETECTION OF MICROMETASTASIS IN LYMPH NODE IN PATIENTS WITH ESOPHAGEAL CANCER

[目的]通过食管癌淋巴结微转移的检测,探讨食管癌淋巴结转移规律。[方法]对某医院2002～2004年间50例pN0食管鳞癌病人的淋巴结病理切片150张,根据淋巴结原发部位进行分组,单抗CK5&6免疫组化染色,比较不同部位淋巴结微转移的差异。[结果]微转移阳性检测率达12%,病灶旁淋巴结微转移阳性率最高,分别为21.7%和20%。左喉返神经旁淋巴结16.7%,胃左及小网膜淋巴结10.3%,隆突下淋巴结的阳性率最低,2%。[结论]胸段食管癌淋巴结微转移最常见的部位是病灶旁和左喉返神经旁,食管癌手术中应注意上述部位淋巴结的清扫。

[Objective] To investigate the micrometastasis in lymph nodes and explore the metastasis pattern of lymph node in patients with esophageal cancer. [ Methods] 150 pieces of pathological sections of lymph node obtained from 50 patients with pN0 esophageal cancer were retrospectively collected to investigate the micrometastasis by using CK5＆6 mon-antibody. All sections were divided by the original location of lymph node in patients to compare the significant difference among groups, [Results] Positive ratio of all micrometastasis was 12%. The highest positive ratio of micrometastasis found in lymph nodes near by the nidus was 21.7% and 20% respectively, near by left recurrent laryngeal nerve 16.7%, near by left gastric arteria and lesser omentum 10.3%; and the least positive ratio found in carina lymph node was 2%. [Conclusion] Lymph nodes near by the nidus and the left recurrent laryngeal nerve are the frequent micrometastasis position in patients with esophageal cancer, lymph node dissection must be made carefully in these regions.