代谢综合征对中老年原发性高血压患者左心室影响的临床观察

Influence of metabolic syndrome on left ventricle in elderly patients with hypertension

目的探讨代谢综合征（MS）对中老年原发性高血压（EH）患者左心室肥厚（LVH）的影响。方法选择门诊中老年EH患者76例，测定其血压、血脂、血糖等，计算体质指数（BMI）。分为单纯高血压组（EH组）及高血压并发MS组（HMS组），用彩色多普勒超声诊断仪，利用二维超声心动图检测室间隔厚度（IVS）、左心室后壁厚度（LVPW）、左心室舒张末期内径（LVDd），计算出左心室心肌重量指数（LVMI）。选择健康人30例作为对照组。结果EH组IVS、LVPW、LVDd、LVMI、LVH发生率高于对照组（均P〈0．05）。HMS组的IVS、LVPW、I．VM、LVMI及LVH发生率高于对照组，亦显著高于EH组（均P〈0．01）。结论高血压患者如并发代谢综合征，LVH则更明显。

Objective To observe the influence of metabolic syndrome （MS） on the left ventricular hypertrophy（LVH） in the essential hypertension（EH） patients. Methods 76 EH patients in middle to advanced ages were selected. Clinical examinations including blood pressure , serum lipid , plasma glucose and body mass index （ BMI ） were performed. The patients were divided into EH group and essential hypertension with HMS group. The left ventricular posterior wall thickness （LVPW） , the left ventricular end diastolic dimension （LVDd） , and interventricular septal thickness （IVS） were detected. The left ventricular mass index （LVMI） was calculated after Doppler and 30 controls were observed. Results LVPW, IVS, LVDd, LVMI and the rate of LVH were obviously higher in EH patients than that in the controls （ P 〈 0.05 ） , and these were also higher in HMS than that in the controls and the EH patients （ P 〈 0.01 ）. Conclusions The degree of the left ventricular hypertrophy in EH patients with metabolic syndrome is more severe than that in EH patients.