代谢综合征与2型糖尿病慢性并发症的相关性

Relationship of metabolic syndrome with diabetic chronic complications in T2DM

目的分析2型糖尿病(T2DM)住院病人代谢综合征(MS)的患病率及其对糖尿病慢性并发症患病率的影响。方法收集579名T2DM住院病人病历资料,统计糖尿病慢性并发症和MS患病率,并按是否合并MS分组,比较其糖尿病慢性并发症的患病率。结果579例中454例合并MS(78.41%),女性明显高于男性(χ2=25.58,P<0.01)。MS组糖尿病肾病(DN,χ2=21.58,P<0.01)和糖尿病大血管并发症(χ2=5.79,P<0.05)的患病率明显高于无MS组。结论合并MS组较无MS组糖尿病大血管并发症和DN的患病率显著升高。

Objective To assess the prevalence of metabolic syndrome （MS） and the relationship between metabolic syndrome and diabetic chronic complications of T2DM among inpatients Methods 579 inpatients with T2DM were selected. Demographic data and a detailed clinical and laboratory examination results were collected. The prevalence of MS in hospitalized patients with T2DM was checked and the association of a component number of MS with chronic diabetic complications was analyzed. The T2DM was grouped by combination with or without metabolic syndrome in comparison of the prevalence of diabetic chronic complications among these groups. Results The prevalence of MS in patients with T2DM was 78.41%,it was higher in women than in men （85. 96% ws 68. 53% ,Xz ：25.58,P〈0.01）. The prevalences of diabetic nephropathy （41.9 % ws 19.2 %, X^2 = 21.58, P 〈 0.01 ） and macrovascular complications （59.2 % ws 47.2 %, X2 = 5. 788, P（0.05）were significantly higher in those with MS than in those without MS. Conclusions The prevalence of diabetic chronic complications is significantly higher in those with MS than in those without MS.