灭活自体骨瓣修补颅骨缺损的临床研究

Repair of skull defect with inactivated autogenous bone flap

目的探讨应用灭活自体颅骨瓣修补颅骨缺损的治疗效果。方法对18例颅骨缺损患者应用灭活自体颅骨瓣二期颅骨缺损修补。结果本组无感染或排斥反应病例，切口均甲级愈合，1例术后皮下积液。术后随访12—24个月，17例修补骨瓣固定，外观满意，1例骨瓣局部吸收并塌陷。结论应用灭活自体颅骨瓣修补颅骨缺损，取材方便，操作简单，费用低廉，并发症少，外观恢复原貌，达到颅骨表面局部解剖重建要求，是颅骨缺损有效可行的治疗方法之一。

Objective To explore the method of repairing skull defect with inactivated autogenous cranial bone flap. Methods Eighteen patients with skull defect underwent secondary repair with inactivated autogenous cranial bone flap. Results No infection and reject reaction were observed and the incision healed up well in all the patients of this group except that subcutaneous hydrops was observed in one patient. Observations during up to 12 -24 months of postoperative follow-up revealed that the bone flap was fixed and had a good appearance in 17 patients ,and that the bone flap was absorbed locally and subsided in one patient. Conclusion Repair of skull defect with inactivated autogenous cranial bone flap is convenient for drawing materials,simple in manipulation and cheap at expenses with less eomplieatlons and good appearance. This operation can fulfil the requirements of reconstructing the surface topography of the skull. Therefore, it is one of the effective and practicable treatments for skull defect.