丁咯地尔治疗糖尿病周围神经病变30例疗效观察

Effect observation of Buflomedil Hydrochloride Injection on the treatment of diabetic peripheral neuropathy

目的观察丁咯地尔治疗糖尿病周围神经病变（DPN）的疗效。方法将60例糖尿病周围神经病变病人随机分为两组，每组各30例。治疗组采用丁咯地尔注射液治疗，对照组采用丹参注射液治疗，观察丁咯地尔注射液对DPN病人症状及肌电图影响。结果治疗组显效率60．0％（18／30），总有效率为90．0％（27／30）；对照组显效率20．0％（6／30）；总有效率为60．0％（18／30）；两组比较有非常显著的统计学意义（P〈0．01）。结论丁咯地尔注射液治疗DPN有较好疗效。

Objective To evaluate the curative effect of Buflomedil Hydrochloride Injection for treating diabetic peripheral neuropathy. Methods 60 cases with diabetic peripheral neuropathy were randomly divided into two groups, 30 cases in each group. Treatment group was administered Buflomedil Hydrochloride Injection, while control group received Salvia Injection. Then the changes of symptom and electromyography in two groups were analyzed. Results In the treatment group, the obvious effective rate was 60.0%（18/30）, and total effective rate was 90.0%（27/30）. In the control group, the obvious effective rate was 20.0%（6/30）, and total effective rate was 60.0%（18/30）. There was statistically significant difference between two groups （P〈0.01）. Conclusions Buflomedil Hydrochloride Injection has a better and confirmed effect in the treatment of diabetic peripheral neuropathy.